Genetic Variations in Vesicoureteral Reflux Sequelae

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Genetic Variations in Vesicoureteral Reflux Sequelae.

Urinary tract infections (UTI) are a common condition in children. Vesicoureteral reflux (VUR) represents a common associated condition with childhood UTI. UTI susceptibility appears to have a genetic component based on family and UTI cohort studies. Targeted analysis of innate immune system genetic variations indicate that these variations are important in UTI susceptibility. In this overview,...

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Vesicoureteral reflux.

Vesicoureteral reflux (VUR), the retrograde flow of urine from the bladder toward the kidney, is common in young children. About 30% of children with urinary tract infections will be diagnosed with VUR after a voiding cystourethrogram. For most, VUR will resolve spontaneously; 20% to 30% will have further infections, but few will experience long-term renal sequelae. Developmentally, VUR arises ...

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Vesicoureteral reflux.

Vesicoureteral reflux, the abnormal flow of urine from the bladder into the ureter, is one of the most common congenital anomalies found in children. The association of vesicoureteral reflux with urinary tract infections and renal scarring has important clinical implications. New insights into pathogenesis and new surgical techniques are changing the approach to the management of this disorder.

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Genetics of Vesicoureteral Reflux

Vesicoureteral reflux (VUR) is the retrograde passage of urine from the bladder to the upper urinary tract. It is the most common congenital urological anomaly affecting 1-2% of children and 30-40% of patients with urinary tract infections. VUR is a major risk factor for pyelonephritic scarring and chronic renal failure in children. It is the result of a shortened intravesical ureter with an en...

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Primary Vesicoureteral Reflux in Children in Southern Iran

Background: Experience with vesicoureteral reflux (VUR) differs in different centers and there is plenty of controversies.Objective: To evaluate the outcome of primary VUR complications and the rate of recurrence of UTI.Methods:  In a retrospective study, the medical charts of all infants and children with primary VUR who were followed up by one nephrologist were reviewed.  During 16 years, 271...

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ژورنال

عنوان ژورنال: Pathogens

سال: 2016

ISSN: 2076-0817

DOI: 10.3390/pathogens5010014